I do not quite understand why you dont believe anything over low risk can have a 95% 5year BCF. Right dose, volume and ADT can achieve it regardless of fractionation (POP RT, WPRT arm)
I do - I think we'll get there. I think we've settled for 85% and shifted priorities - if we optimize dose, 90% is floor today and likely closer to 93% through most IR disease without ADT. Step two is pushing HR and as you say selectively using ADT to get nearly all up around 95% - that would simply be great.
But we need the higher end of our EQD2 doses today and we need should eliminate the lower ones for most IR disease - I think we can do that safely today - at least that is what I think the long-term data will show. But I've been wrong before.
Very well summarised!
I do not quite understand why you dont believe anything over low risk can have a 95% 5year BCF. Right dose, volume and ADT can achieve it regardless of fractionation (POP RT, WPRT arm)
I do - I think we'll get there. I think we've settled for 85% and shifted priorities - if we optimize dose, 90% is floor today and likely closer to 93% through most IR disease without ADT. Step two is pushing HR and as you say selectively using ADT to get nearly all up around 95% - that would simply be great.
But we need the higher end of our EQD2 doses today and we need should eliminate the lower ones for most IR disease - I think we can do that safely today - at least that is what I think the long-term data will show. But I've been wrong before.
Thanks again for reading.